Augmentin Intravenous - - (e. MC)This information is intended for use by health professionals. Each vial contains sodium amoxicillin equivalent to 5.
Excipients with known effect: Sodium 3. Potassium 1. 9. 6 mg (0. Each vial or bottle contains sodium amoxicillin equivalent to 1.
Excipients with known effect: Sodium 6. Potassium 3. 9. 3 mg (1. For the full list of excipients, see section 6.
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Powder for solution for injection or infusion. Vials containing a white to off- white sterile powder.
Powder for solution for injection or infusion. Vials or bottles containing a white to off- white sterile powder. Augmentin is indicated for the treatment of the following infections in adults and children (see sections 4. Severe infections of the ear, nose and throat (such as mastoiditis, peritonsillar infections, epiglottitis, and sinusitis when accompanied by severe systemic signs and symptoms)• Acute exacerbations of chronic bronchitis (adequately diagnosed)• Community acquired pneumonia• Cystitis• Pyelonephritis• Skin and soft tissue infections in particular cellulitis, animal bites, severe dental abscess with spreading cellulitis• Bone and joint infections, in particular osteomyelitis• Intra- abdominal infections• Female genital infections. Prophylaxis against infections associated with major surgical procedures in adults, such as those involving the: • Gastrointestinal tract• Pelvic cavity• Head and neck• Biliary tract surgery.
Consideration should be given to official guidance on the appropriate use of antibacterial agents. Yellow Face Place Dating there. Posology. Doses are expressed throughout in terms of amoxicillin/clavulanic acid content except when doses are stated in terms of an individual component. The dose of Augmentin that is selected to treat an individual infection should take into account: • The expected pathogens and their likely susceptibility to antibacterial agents (see section 4. The severity and the site of the infection • The age, weight and renal function of the patient as shown below. The use of alternative presentations of Augmentin (e. This Augmentin powder for solution for injection or infusion provides a total daily dose of 3. If it is considered that a higher daily dose of amoxicillin is required it is recommended that an alternative intravenous formulation of Augmentin is selected in order to avoid administration of unnecessarily high daily doses of clavulanic acid.
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The duration of therapy should be determined by the response of the patient. Some infections (e. Treatment should not be extended beyond 1. Consideration should be given to local guidelines on appropriate dosing frequencies for amoxicillin/clavulanic acid. Adults and children ≥ 4.
For treatment of infections as indicated in section 4. For surgical prophylaxis. For procedures less than 1 hour in duration, the recommended dose of Augmentin is 1.
Doses of 2. 00. 0 mg/2. Augmentin). For procedures greater than 1 hour in duration, the recommended dose of Augmentin is 1. Clear clinical signs of infection at operation will require a normal course of intravenous or oral therapy post- operatively. Children < 4. 0 kg. Recommended doses: • Children aged 3 months and over: 2. Children aged less than 3 months or weighing less than 4 kg: 2.
Elderly. No dose adjustment is considered necessary. Renal impairment Dose adjustments are based on the maximum recommended level of amoxicillin. No dose adjustment is required in patients with creatinine clearance (Cr. Cl) greater than 3. Adults and children ≥ 4. Cr. Cl: 1. 0- 3. 0 ml/min. Initial dose of 1.
Cr. Cl < 1. 0 ml /min. Initial dose of 1. Haemodialysis. Initial dose of 1. Children < 4. 0 kg Cr. Cl: 1. 0 to 3. 0 ml/min. Cr. Cl < 1. 0 ml /min. Haemodialysis. 2.
Hepatic impairment. Dose with caution and monitor hepatic function at regular intervals (see sections 4.
Method of administration. Augmentin is for intravenous use. Augmentin may be administered either by slow intravenous injection over a period of 3 to 4 min directly into a vein or via a drip tube or by infusion over 3. Augmentin is not suitable for intramuscular administration. Children aged less than 3 months should be administered Augmentin by infusion only.
Treatment with Augmentin may be initiated by the use of an intravenous preparation and completed with an appropriate oral presentation as considered appropriate for the individual patient. For instructions on reconstitution and dilution of the medicinal product before administration, see section 6. Hypersensitivity to the active substances, to any of the penicillins or to any of the excipients listed in section 6. History of a severe immediate hypersensitivity reaction (e. History of jaundice/hepatic impairment due to amoxicillin/clavulanic acid (see section 4. Before initiating therapy with amoxicillin/clavulanic acid, careful enquiry should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins, or other beta- lactam agents (see sections 4.