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ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults. Table of Contents. Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk S2. Introduction S3. 1. Organization of the Panel S3. Document Review and Approval S3. Scope of Guideline S3.
Methodology and Evidence Review S5. Overview of the Guideline S6. Lifestyle as the Foundation for ASCVD Risk- Reduction Efforts S6. Initiation of Statin Therapy S7. Critical Questions and Conclusions S1. Identification of CQs S1.
CQ1: LDL- C and Non–HDL- C Goals in Secondary Prevention S1. CQ2: LDL- C and Non–HDL- C Goals in Primary Prevention S1. CQ3: Efficacy and Safety of Cholesterol- Lowering Medications S1. Statin Treatment: Recommendations S1.
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Cholesterol is essential for life, but high blood cholesterol can increase a person's risk of heart disease and stroke. A cholesterol test may be used alone or as. CHOLESTEROL LEVELS / CHOLESTROL LEVELS Also known as cholesterol numbers or cholesterol ratings. Just wondering how high your cholesterol level really is?
Intensity of Statin Therapy in Primary and Secondary Prevention S1. LDL- C and Non–HDL- C Treatment Goals S1. Secondary Prevention S1. Primary Prevention in Individuals ≥2.
- Original Article. HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events. Anand Rohatgi, M.D., Amit Khera, M.D., Jarett D. Berry, M.D., Edward G. Givens.
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- Cholesterol is essential to your health. Simple lifestyle choices may reduce your risk for heart disease without the additional health risks.
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- Previously, in Part I, Part II, Part III, Part IV, Part V,and Part VI of this series, we addressed these 8 concepts: #1 — What is cholesterol?
Years of Age With LDL- C ≥1. L S1. 44. 5. Primary Prevention in Individuals With Diabetes S1. Primary Prevention in Individuals Without Diabetes and With LDL- C 7. L S1. 64. 7. Risk Assessment in Primary Prevention S1. Heart Failure and Hemodialysis S1. Safety: Recommendations S1.
Managing Statin Therapy: Recommendations S2. Monitoring Statin Therapy S2.
Optimizing Statin Therapy S2. Insufficient Response to Statin Therapy S2. Testing S2. 16. 3. Nonstatins Added to Statins or in Statin- Intolerant Individuals S2.
Selected Clinical and Population Subgroups S2. Sex and Racial and Ethnic Subgroups S2. Individuals > 7.
Years of Age S2. 38. Limitations S2. 49. Evidence Gaps and Future Research Needs S2. Conclusions S2. 4References S2. Appendix 1. Author Relationships With Industry and Other Entities (Relevant) S2. Appendix 2. Expert Reviewer Relationships With Industry and Other Entities S3.
Appendix 3. Abbreviations S3. Appendix 4. Evidence Statements S3. Appendix 5. Expanded Discussion of What’s New in the Guideline S4. Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk. The goals of the American College of Cardiology (ACC) and the American Heart Association (AHA) are to prevent cardiovascular diseases; improve the management of people who have these diseases through professional education and research; and develop guidelines, standards, and policies that promote optimal patient care and cardiovascular health. Toward these objectives, the ACC and AHA have collaborated with the National Heart, Lung, and Blood Institute (NHLBI) and stakeholder and professional organizations to develop clinical practice guidelines for assessment of cardiovascular risk, lifestyle modifications to reduce cardiovascular risk, management of blood cholesterol in adults, and management of overweight and obesity in adults.
In 2. 00. 8, the NHLBI initiated these guidelines by sponsoring rigorous systematic evidence reviews for each topic by expert panels convened to develop critical questions (CQs), interpret the evidence, and craft recommendations. In response to the 2. Institute of Medicine on the development of trustworthy clinical guidelines,1 the NHLBI Advisory Council recommended that the NHLBI focus specifically on reviewing the highest- quality evidence and partner with other organizations to develop recommendations. Accordingly, in June 2.
NHLBI initiated collaboration with the ACC and AHA to work with other organizations to complete and publish the 4 guidelines noted above and make them available to the widest possible constituency. Recognizing that the Expert Panels/Work Groups did not consider evidence beyond 2. ACC, AHA, and collaborating societies plan to begin updating these guidelines starting in 2. The joint ACC/AHA Task Force on Practice Guidelines (Task Force) appointed a subcommittee to shepherd this transition, communicate the rationale and expectations to the writing panels and partnering organizations, and expeditiously publish the documents. The ACC/AHA and partner organizations recruited a limited number of expert reviewers for fiduciary examination of content, recognizing that each document had undergone extensive peer review by representatives of the NHLBI Advisory Council, key federal agencies, and scientific experts. Each writing panel responded to comments from these reviewers.
Clarifications were incorporated where appropriate, but there were no substantive changes because the bulk of the content was undisputed. Although the Task Force led the final development of these prevention guidelines, they differ from other ACC/AHA guidelines. First, as opposed to an extensive compendium of clinical information, these documents are significantly more limited in scope and focus on selected CQs on each topic, based on the highest- quality evidence available. Recommendations were derived from randomized trials, meta- analyses, and observational studies evaluated for quality and were not formulated when sufficient evidence was not available.